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Posted: 2025-05-16 22:16:47 UTC
This article contains some claims that are falsified. While not everything in the article is false, please proceed with extreme caution and verify any critical information independently.
This article contains some claims that are falsified. While not everything in the article is false, please proceed with extreme caution and verify any critical information independently.
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Last Updated
2025-05-16 22:18:53 UTC
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Rollup News
This thread discusses the neuroanatomical aspects of Borderline Personality Disorder (BPD) in recognition of BPD Awareness Day, highlighting the brain structures involved and current evidence.
Amygdala: Hyperactivation, especially on the left side, with exaggerated reactivity to ambiguous signals.
Hippocampus: Reduced volume and abnormal activation, leading to deficits in episodic memory and heightened response to social rejection.
Prefrontal Cortex: Hypoactivity and decreased gray matter, impairing emotional regulation and analysis.
Insula: Hyperactivation contributing to heightened bodily awareness, emotional intensity, and anxiety.
Cingulate Cortex: Anterior part is hypoactive (emotion), posterior part is hyperactive (alert), altering the circuit with the amygdala and orbitofrontal cortex.
Nucleus Accumbens: Hipoactivity related to reduced pleasure, motivation, and difficulty in experiencing stable emotional satisfaction.
Temporal and Occipital Lobes: Reduced blood flow and activation, leading to difficulties in interpreting gestures.
White Matter and Corpus Callosum: Decreased volume, especially in the right hemisphere, and reduced connectivity between fronto-temporal regions.
Intense emotions
Impulsivity
Unstable relationships
Self-harm
Risk of suicide
Difficulty regulating emotions
Poor interpretation of emotions
Difficulty feeling stable emotional satisfaction
Difficulties in interpreting gestures