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Posted: 2025-04-12 02:49:29 UTC
This article contains some claims that remain unverified. While much of the content may be accurate, exercise care when relying on this information.
This article contains some claims that remain unverified. While much of the content may be accurate, exercise care when relying on this information.
Status
Last Updated
2025-04-12 02:49:48 UTC
Verified By
Rollup News
This study explores enhancing CAR T cell therapy by engineering CAR T cells to secrete TGFβtrap, IL15, or IL12 molecules fused to αPDL1 scFv, aiming to improve tumor-localized immunomodulation and CAR T cell functionality.
Enhancing CAR T cell therapy
Tumor-localized immunomodulation
Improving CAR T cell functionality
TGFβtrap, IL15, or IL12 molecules fused to αPDL1 scFv