SIRT5 Protects Against Primate Skeletal Muscle Aging

Posted: 2025-04-17 19:21:42 UTC

@Nature MetabolismNatMetabolism

#muscle

#SIRT5

#primate

#ageing

#desuccinylation

#inflammatory

#senescent

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This article contains some claims that remain unverified. While much of the content may be accurate, exercise care when relying on this information.

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2025-04-17 19:21:58 UTC

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SIRT5 protects against primate skeletal muscle aging through TBK1 desuccinylation, inhibiting downstream inflammatory and senescent phenotypes.

SIRT5 role in protecting against skeletal muscle aging

TBK1 desuccinylation as a key mechanism

Inhibition of inflammatory and senescent phenotypes