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Posted: 2025-04-17 19:50:40 UTC
This article contains some claims that remain unverified. While much of the content may be accurate, exercise care when relying on this information.
This article contains some claims that remain unverified. While much of the content may be accurate, exercise care when relying on this information.
Status
Last Updated
2025-04-17 19:50:56 UTC
Verified By
Rollup News
This study reveals that the cytokine IL-6 enhances USP24 expression via STAT3/NF-κB signaling, leading to PD-1 deubiquitination and stabilization, which impacts tumor immunity.
IL-6 drives USP24 expression
STAT3/NF-κB signaling pathway
PD-1 deubiquitination and stabilization
Tumor immunity modulation
Understanding the precise mechanisms of PD-1 regulation in the tumor microenvironment.
Identifying novel therapeutic targets to enhance anti-tumor immunity.