Z=LKH!BFA%^=+S?'-Q_[,@L0Z/&I-F
SYSTEM PROCESSING...
Z=LKH!BFA%^=+S?'-Q_[,@L0Z/&I-F
SYSTEM PROCESSING...
Posted: 2025-04-23 06:50:01 UTC
This article contains some claims that remain unverified. While much of the content may be accurate, exercise care when relying on this information.
This article contains some claims that remain unverified. While much of the content may be accurate, exercise care when relying on this information.
Status
Last Updated
2025-04-23 06:50:26 UTC
Verified By
Rollup News
This study investigates the impact of using earlier, unfractionated stem cell products on CAR-T cell function and mitochondrial fitness in multiple myeloma treatment. It compares early (mobHCT) T-cells collected before transplant with late (aphCAR) T-cells collected after multiple treatment lines, highlighting differences in CD4:CD8 ratios, expansion, exhaustion, IL2 levels, killing ability, and mitochondrial function.
Enhanced CAR-T cell function
Improved mitochondrial fitness
Earlier stem cell product benefits
Multiple myeloma treatment
T-cell exhaustion
Mitochondrial dysfunction