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Posted: 2025-04-24 05:06:22 UTC
This article contains some claims that remain unverified. While much of the content may be accurate, exercise care when relying on this information.
This article contains some claims that remain unverified. While much of the content may be accurate, exercise care when relying on this information.
Status
Last Updated
2025-04-24 05:06:47 UTC
Verified By
Rollup News
This translational research explores the effectiveness of VEGF-A EV therapy in promoting new vessel formation within murine models suffering from ischaemic vascular disease.
VEGF-A mRNA delivered via VEGF-A EVs significantly increased protein expression.
VEGF-A EVs promoted enhanced neovascularization in ischaemic tissue.
VEGF-A EVs elicited reduced immune activation compared to other nucleic acid delivery modalities.
EVs loaded with VEGF-A mRNA may offer an effective and potentially safer path for delivering angiogenic gene therapy to ischaemic tissue.
Ischaemic vascular disease
Effective delivery of angiogenic gene therapy